
Introduction
Samantha’s practice focuses on mergers and acquisitions, private company transactions, and corporate governance. She represents clients across a range of industries, including technology, professional services, and healthcare, guiding them through complex business transactions, regulatory compliance, and governance matters. With extensive experience in transactional law, Samantha helps businesses navigate acquisitions, divestitures, joint ventures, and other high-stakes deals, delivering practical legal counsel from initial structuring through closing.
My focus
MERGERS & ACQUISITIONS
I represent both buyers and sellers in the purchase and sale of businesses in a wide variety of industries including, technology companies, life sciences, healthcare services and providers, and food and beverage. My work includes cross-industry M&A, deal structuring, due diligence, and negotiation of transaction demands.
GENERAL CORPORATE
I represent clients in the negotiation and preparation of a wide variety of commercial agreements. I also assist clients with entity formations, corporate structuring and restructuring, and the dissolution or winding down of their business. For healthcare clients, this often includes structuring arrangements to align with industry regulations and compliance requirements.
PRIVATE EQUITY
Most recently, my practice has honed in on advising on, and assisting healthcare clients in the implementation and use of a management service organizations (MSOs) or the “friendly PC” model and other internal restructuring systems as part of preparing businesses for private equity-backed acquisitions and other M&A transactions.
Looking ahead
Evolving market dynamics, heightened regulatory scrutiny, and shifting capital conditions continue to reshape how transactions are sourced, structured, and integrated across industries. I continue to monitor these changes and prepare for what’s next by anticipating legal guardrails and integration risks, aligning M&A strategies with client business goals, and delivering efficient, compliant execution that positions healthcare organizations and companies across industries for growth or successful exits.
In the news
- Corporate Counsel
Corporate Counsel announces finalists for its 2025 Women, Influence & Power in Law Awards
Aug 4, 2025This article announcing the finalists for the 2025 Women, Influence & Power in Law Awards highlights Boston Corporate partner Amy O’Keefe, co-leader of NP’s Women in Dealmaking initiative, as a finalist in the “Law Firm Collaborative Leadership” category, and Long Island Healthcare partner Michele Masucci and associate Samantha Barbere as finalists in the “Law Firm Mentor & Mentee Collaboration” category. The WIPL awards recognize in-house and law firm women leaders and allies who have demonstrated a commitment to advancing the empowerment of women in law.
Admitted to practice
New York
Education
Maurice A. Deane School of Law, Hofstra University, J.D., cum laude
Long Island University, B.A., magna cum laude
Recognition
- Selected, through a peer-review survey, for inclusion in Best Lawyers: Ones to Watch 2026 in the field of Corporate Law; listed in Best Lawyers: Ones to Watch since 2024
- Recognized, The M&A Advisor 2025 Emerging Leaders Award
- Finalist, ALM Law Women, Influence & Power in Law Awards 2025 for Mentor & Mentee Collaboration with Michele Masucci (Mentor) and Samantha (Mentee)




